Medical College Admission Test

The Medical College Admission Test (MCAT) is a standardized, computer-based exam used by medical schools to evaluate readiness for medical education. It assesses foundational science knowledge as well as critical analysis and reasoning. Use the 10-section framework on this page to plan study, revise systematically, and practice by topic.

Owner: AAMC Credential: Medical College Admission Test (MCAT) Exam: MCAT Core sections: Chem/Phys, CARS, Bio/Biochem, Psych/Soc

MCAT exam syllabus coverage (10-section study plan)

Master high-yield MCAT content and practise MCAT-style thinking. The MCAT is passage-based: success depends on combining core knowledge with critical reasoning, data interpretation, and efficient reading.

  • Aligned to the MCAT’s core competencies: scientific foundations, reasoning with data, and critical reading (CARS).
  • Use the science sections to master concepts, then practise translating them into passage-based problem solving.
  • Use the CARS section to drill passage mapping, argument structure, assumptions, and inference.
  • Use this page as a structured checklist before full-length practice exams and timed mixed sets.

Use the Practice this section button on each card to open the question bank for that syllabus area in a new tab.

General Chemistry Foundations

S01

What you will practice:

High-yield coverage of General Chemistry Foundations concepts and MCAT-style applications across core subdomains.

  • Atomic structure: isotopes, average atomic mass, and mass spectrometry interpretation.
  • Quantum model, quantum numbers, orbital shapes, and electron configuration rules (Aufbau, Hund, Pauli).
  • Periodic trends: atomic/ionic radius, ionization energy, electron affinity, electronegativity, shielding, effective nuclear charge.
  • Bonding and structure: ionic vs covalent character, polarity, Lewis structures, resonance, formal charge, bond order.
  • Molecular geometry (VSEPR), hybridization, dipoles, and intermolecular forces.
  • Stoichiometry: moles, limiting reagents, percent composition, empirical vs molecular formulas.
  • Reaction types: redox, acid-base, precipitation, titrations and quantitative calculations.
  • Gases and kinetic molecular theory; ideal vs real gases and common gas laws.
  • Solutions: concentration units, solubility rules, Ksp, colligative properties, osmosis and Raoult’s law.
  • Thermodynamics, kinetics, and equilibrium: ΔH, ΔS, ΔG, Hess’s law, rate laws, Arrhenius, K, Q, and Le Chatelier.
  • Acids/bases: Brønsted-Lowry vs Lewis, pH/pKa, buffers, Henderson-Hasselbalch, titration curves, polyprotic systems.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Organic Chemistry

S02

What you will practice:

High-yield coverage of Organic Chemistry concepts and MCAT-style applications across core subdomains.

  • Functional groups and nomenclature; constitutional isomers and conformational ideas.
  • Stereochemistry: chirality, enantiomers vs diastereomers, R/S configuration, optical activity.
  • Hydrocarbons: alkanes, alkenes, alkynes; stability trends and typical reactions.
  • Aromaticity and benzene chemistry; directing effects at a high level.
  • Alcohols and ethers: synthesis concepts; oxidation/reduction of alcohols; epoxides and ring opening logic.
  • Carbonyl chemistry: aldehydes, ketones, carboxylic acids and derivatives (esters, amides, anhydrides).
  • Core mechanisms: nucleophile/electrophile logic, leaving groups, acid/base effects on pathways.
  • Substitution and elimination: SN1/SN2, E1/E2, stereochemical outcomes and competing pathways.
  • Carbocation stability, rearrangements, and common mechanistic patterns.
  • Lab techniques: IR, NMR, mass spectrometry; chromatography, extraction, and distillation.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Biochemistry

S03

What you will practice:

High-yield coverage of Biochemistry concepts and MCAT-style applications across core subdomains.

  • Amino acids: structure, properties, classification, acid-base behavior, and isoelectric point.
  • Peptides/proteins: peptide bond, levels of structure, folding forces, disulfide bonds, denaturation.
  • Enzymes: Michaelis-Menten kinetics (Km, Vmax), catalytic efficiency and regulation.
  • Inhibition types (competitive, noncompetitive) and allosteric control; zymogens.
  • Carbohydrates: mono/di-saccharides, stereochemistry basics, glycosidic bonds, glycogen vs starch.
  • Lipids: fatty acids, triglycerides, phospholipids, steroids; membranes and fluidity.
  • Metabolism overview: glycolysis, pyruvate oxidation, TCA cycle, ETC and oxidative phosphorylation.
  • Pathways integration: PPP, gluconeogenesis, fatty acid synthesis, β-oxidation, ketone bodies.
  • Molecular biology: DNA replication, transcription, translation and gene regulation.
  • Biotech methods: PCR, gel electrophoresis, recombinant DNA and mutation consequences.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Physics for Biological Systems

S04

What you will practice:

High-yield coverage of Physics for Biological Systems concepts and MCAT-style applications across core subdomains.

  • Kinematics, Newton’s laws, free-body reasoning, and common biological applications.
  • Work, energy, power, and conservation principles; potential/kinetic energy transformations.
  • Momentum and impulse; collisions and center-of-mass reasoning.
  • Fluids: density, pressure, buoyancy; continuity and Bernoulli in physiological contexts.
  • Viscosity and laminar flow; Poiseuille flow and analogies to blood circulation.
  • Waves: frequency, wavelength, superposition; standing waves and resonance basics.
  • Sound and Doppler effect; qualitative ultrasound concepts.
  • Electrostatics: electric charge, fields, potential, and capacitance ideas.
  • Circuits: resistance, Ohm’s law, Kirchhoff’s rules and capacitor behavior.
  • Optics: reflection, refraction, lenses/mirrors, magnification, and human eye basics.
  • Atomic/nuclear: decay, half-life, binding energy and common imaging/medical applications.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Cell Biology

S05

What you will practice:

High-yield coverage of Cell Biology concepts and MCAT-style applications across core subdomains.

  • Cell structure and organelle function; membrane composition and the fluid mosaic model.
  • Cytoskeleton components and roles in cell shape, movement, and transport.
  • Membrane transport: diffusion, facilitated diffusion, active transport and secondary active transport.
  • Vesicular transport: endocytosis, exocytosis and key conceptual drivers.
  • Cell cycle: interphase, mitosis, meiosis, checkpoints, cyclins and CDKs.
  • Apoptosis vs necrosis; intrinsic/extrinsic pathways and caspase cascades.
  • Cell signaling: receptors, G-proteins, tyrosine kinases and second messengers (cAMP, IP3, Ca2+).
  • Bioenergetics: ATP production, chemiosmosis and mitochondrial function.
  • Cell-cell interactions and tissue-level organization concepts.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Human Physiology

S06

What you will practice:

High-yield coverage of Human Physiology concepts and MCAT-style applications across core subdomains.

  • Nervous system: neuron structure, action potentials, synapses and neurotransmitters.
  • CNS vs PNS organization; autonomic nervous system and major divisions.
  • Cardiovascular: heart anatomy, conduction system, cardiac cycle and hemodynamics.
  • Blood vessels, blood pressure regulation and oxygen transport principles.
  • Respiratory: ventilation, gas exchange, hemoglobin binding and control of breathing.
  • Digestive: mechanical vs chemical digestion, absorption, and roles of liver/pancreas.
  • Renal: nephron structure, filtration, reabsorption, secretion and osmoregulation.
  • Acid-base balance and buffering at the organism level.
  • Endocrine: hormone classes, major glands, HPA axis and feedback loops.
  • Immune: innate vs adaptive, B cells vs T cells, antibodies and vaccination principles.
  • Musculoskeletal: sliding filament theory, muscle contraction, and bone physiology.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Genetics and Evolution

S07

What you will practice:

High-yield coverage of Genetics and Evolution concepts and MCAT-style applications across core subdomains.

  • Mendelian inheritance patterns and problem-solving with Punnett squares.
  • Pedigree analysis and interpretation of inheritance modes.
  • Linkage, recombination and mapping intuition at the MCAT level.
  • Gene expression control and epigenetic regulation concepts.
  • Chromosomal abnormalities: nondisjunction, aneuploidy and structural changes.
  • Population genetics: Hardy-Weinberg, drift, gene flow and selection.
  • Evolution: natural selection, adaptation, fitness, and speciation mechanisms.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Psychology

S08

What you will practice:

High-yield coverage of Psychology concepts and MCAT-style applications across core subdomains.

  • Sensation and perception: visual, auditory and somatosensory processing basics.
  • Learning theories: classical conditioning, operant conditioning and observational learning.
  • Memory: encoding, storage, retrieval, and common memory errors/disorders.
  • Cognition: language, intelligence, decision making and problem solving.
  • Motivation and emotion: drives, stress response and major emotion theories.
  • Personality: trait models and psychoanalytic perspectives (high-level).
  • Psychological disorders: mood and anxiety disorders, schizophrenia and related concepts.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Sociology

S09

What you will practice:

High-yield coverage of Sociology concepts and MCAT-style applications across core subdomains.

  • Culture, norms, values and socialization processes.
  • Social structure: institutions, roles, status and social stratification.
  • Demographics: population growth, migration and urbanization.
  • Social inequality: race, gender, class and health disparities.
  • Group behavior: conformity, obedience, social identity and group dynamics.
  • Healthcare and society: access to care, epidemiology and public health models.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

Critical Analysis and Reasoning Skills

S10

What you will practice:

High-yield coverage of Critical Analysis and Reasoning Skills concepts and MCAT-style applications across core subdomains.

  • Active reading for CARS: passage mapping, main idea and structure tracking.
  • Author intent, tone and viewpoint; distinguishing claims from evidence.
  • Argumentation: identifying premises, conclusions and assumptions.
  • Evaluating evidence quality; detecting flaws and alternative explanations.
  • Inference: deriving implicit conclusions while avoiding overreach.
  • Strengthen/weaken and reasoning-within-the-text strategies.
  • Humanities and social sciences contexts: philosophy, ethics, literature and political theory.

Tip: After topic practice, do mixed sets under time pressure and review missed questions immediately.

FAQ

What does the MCAT test?

The MCAT tests foundational concepts in the natural sciences, biochemistry, biology, psychology and sociology, alongside Critical Analysis and Reasoning Skills (CARS). Much of the exam is passage-based, so you must apply knowledge to interpret data, evaluate evidence, and reason through unfamiliar scenarios.

How should I use these 10 sections if the MCAT has 4 official sections?

The official MCAT sections are Chem/Phys, CARS, Bio/Biochem, and Psych/Soc. This page breaks the underlying content into 10 balanced study sections so you can plan coverage and practise weaker areas with precision, while still building mixed practice that mirrors the real exam.

Which areas tend to be most time-sensitive?

CARS is the most time-pressured for many students because it is purely reading and reasoning. In the science sections, speed improves when you are fluent with high-yield formulas, units, graphs, and experimental design patterns.

What is the best practice sequence?

Start with content mastery by section, then transition to passage-based practice and mixed sets. Use error logs to identify recurring gaps (conceptual, calculation, or reasoning), and revisit the relevant section cards on this page for targeted revision.